Medical calculators

4Ts Score

Heparin-Induced Thrombocytopenia

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How it is calculated

HIT is a prothrombotic disorder despite the low platelets - the danger is clot, not bleeding, so the answer is switching anticoagulant rather than stopping anticoagulation. Platelet transfusion is avoided. Warfarin must not be started alone in acute HIT, because it can precipitate venous limb gangrene.

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Probability that thrombocytopenia on heparin is immune-mediated. The danger in HIT is clotting, not bleeding.

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