Medical calculators

Modified Duke Criteria

Infective Endocarditis

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How it is calculated

Modified Duke criteria. Definite requires 2 major, or 1 major and 3 minor, or 5 minor. Major: typical organism in two separate cultures (or persistently positive cultures, or a single positive for Coxiella burnetii), and evidence of endocardial involvement on echo or a new regurgitant murmur. Minor: predisposing heart condition or injecting drug use, fever above 38 degrees C, vascular phenomena, immunological phenomena, and microbiological evidence not meeting a major criterion. Pathological criteria - organisms or lesions demonstrated in the vegetation itself - are definite regardless of this tally.

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Classifies a suspected infective endocarditis as definite, possible or rejected from major and minor criteria. Pathological criteria - organisms in the vegetation itself - are definite regardless of the tally.

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