Medical calculators

SIRS

Inflammatory Response

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How it is calculated

SIRS: temperature >38 or <36 degrees C, heart rate >90, respiratory rate >20 (or PaCO2 <32 mmHg), white cells >12 or <4 x10^9/L (or >10% bands). Superseded by Sepsis-3 in 2016 for defining sepsis, because it is neither sensitive nor specific for that. It remains a recommended screening tool: Surviving Sepsis 2026 prefers SIRS, NEWS2 or MEWS to qSOFA alone for flagging possible sepsis.

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The systemic inflammatory response criteria. Superseded by Sepsis-3 for DEFINING sepsis, but still a recommended screening tool: Surviving Sepsis 2026 prefers SIRS, NEWS2 or MEWS to qSOFA alone.

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